Nitric Oxide

Have you heard of Nitric Oxide (NO)? Nitric oxide is a molecule that our body produces to help its 50 trillion cells communicate with each other by transmitting signals throughout the entire body.

There have been over 60,000 studies done on nitric oxide in the last 20 years and in 1998, The Nobel Prize for Medicine was given to three scientists that discovered the signaling role of nitric oxide.

At the heart of Pro NO10 is L-Arginine. This amino acid is most often associated with heart health. It raises blood levels of nitric oxide (NO), a compound that expands blood vessels, keeps arteries pliable, and enhances blood flow.

Among other great benefits, research has found that taking supplemental arginine improved symptoms of congestive heart failure; other studies suggest it may reduce cholesterol, as well as lower blood pressure in those with hypertension.

Nitric Oxide (NO)

Over 20,000 articles in medical literature since 1980 attest that “absolutely everything in the body depends on Nitric Oxide.” Its function in human physiology is so important that the American Academy of Science named Nitric Oxide the “Molecule of the year” in 1992.

The Nobel Prize in Medicine was awarded to scientists who began the research on Nitric Oxide in 1998 and now NO has been referred to as “The Molecule of the Millennium.” Dr. Jonathan S. Stamler, a professor of medicine at Duke University Medical Center, put it best when he said of Nitric Oxide:

“It does everything, everywhere. You cannot name a major cellular response or physiological effect in which [Nitric Oxide] is not implicated today. It’s involved in complex behavioral changes in the brain, airway relaxation, beating of the heart, dilation of blood vessels, regulation of intestinal movement, function of blood cells, the immune system, even how fingers and arms move.”

Most nitric oxide supplements you see are simply products that contain some form of arginine. You may be familiar with this amino acid due to its potential to increase growth hormone (GH) levels. Arginine also plays a number of other roles in your body, one of them being the production of nitric oxide (NO).

Increased Blood Flow, Helping Oxidative Stress, and More

Nitric Oxide is essentially a signaling molecule that helps control a range of processes in the body, including nerve signaling, immune functions, muscle growth and the dilation of blood vessels. Dilation simply means the opening up of blood vessels, which helps to increase blood flow to your muscles, bringing with it much-needed nutrients, oxygen and hormones (especially if arginine is boosting your GH). It also means enhanced blood flow to other parts of your body, including those that are, shall we say, below the belt. This is why you'll see much evidence of arginine as a libido enhancing aid for both men and women.

The good news is that the scientific research supports arginine's ability to drive NO synthesis, especially in people with high cholesterol, high blood pressure, diabetes, and in those who smoke. Taking supplemental arginine also appears to enhance NO production during wound healing and oxidative stress. Since muscle recovery following exercise is likened to wound healing and oxidative stress increases with exercise, the chances are good that an NO supplement will be beneficial in your muscle-building quest as well.

Perking Up the Libido with Nitric Oxide

Researchers are experimenting with arginine as an alternative to Viagra-like drugs for treating impotence in men and sexual dysfunction in women. In one study of 50 men with erection problems, half swallowed 5 grams of arginine daily while their counterparts took a dummy pill. Six weeks later, a greater number of men in the amino acid group than in the placebo group reported enhanced “sexual performance.” In a similar study of postmenopausal women with lackluster libidos, those taking 6 grams of arginine noted a greater improvement in sexual response than their counterparts on placebos.

Impotence medications work due to their action on nitric oxide. One cause of impotence is unhealthy and aged arteries that feed blood to the sexual organs. Medications, such as Viagra, works by creating more nitric oxide, therefore causing a cascade of enzymatic reactions magnifying and extending nitric oxide, causing more blood flow and positive results.

Pro NO10: A Perfect Formula

You increase nitric oxide most notably by consuming the amino acids L-arginine and L-citrulline. Arginine directly creates nitric oxide and citrulline inside the cell. Citrulline is then recycled back into arginine, making even more nitric oxide. Enzymes that convert arginine to citrulline, and citrulline to arginine need to function optimally for efficient nitric oxide production.

You can protect those enzymes and nitric oxide by consuming healthy foods and antioxidants, such as vitamins C and E, CoQ10, and alpha lipoic acid, allowing you to produce more nitric oxide. Nitric oxide only lasts a few seconds in the body, so the more antioxidant protection we provide, the more stable it will be and the longer it will last. Doctors are utilizing this science by coating stents (mesh tubes that prop open arteries after surgery) with drugs that produce nitric oxide.

A great amount of forethought and clinical work went into developing the strong, extremely comprehensive formula - a powdered drink - for our new Pro NO10.

Coenzyme Q10

Our also includes Coenzyme Q10 (CoQ10).  CoQ10 is a compound found naturally in the energy-producing center of the cell known as the mitochondria.

CoQ10 boosts energy, enhances the immune system, and acts as an antioxidant. A growing body of research suggests that using Coenzyme Q10 supplements alone or in combination with other nutritional supplements may help prevent or treat some conditions such as heart disease, high cholesterol, and high blood pressure.

Researchers believe that the beneficial effect of CoQ10 in the prevention and treatment of heart disease is due to its ability to improve energy production in cells, inhibit blood clot formation, and act as an antioxidant. One important study, for example, found that people who received daily CoQ10 supplements within 3 days of a heart attack were significantly less likely to experience subsequent heart attacks and chest pain. In addition, these same patients were less likely to die of heart disease than those who did not receive the supplements.

Levels of CoQ10 tend to be lower in people with high cholesterol compared to healthy individuals of the same age. In addition, certain cholesterol-lowering drugs called statins (such as atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin) appear to deplete natural levels of CoQ10 in the body. Taking CoQ10 supplements can correct the deficiency caused by statin medications without affecting the medication's positive effects on cholesterol levels.

CoQ10 supplements may improve heart health and blood sugar and help manage high cholesterol and high blood pressure in individuals with diabetes. (High blood pressure, high cholesterol, and heart disease are all common problems associated with diabetes).

Nitric Oxide And Heart Disease